Riccardo Calafiori was attributable to start for Arsenal against Wigan Athletic within the FA Cup on Sunday but was injured within the warm-up.
The Italian has struggled with injury issues this season, but was considered able to play within the fourth round on the Emirates on Sunday afternoon.
Calafiori was attributable to start at left-back, with Myles Lewis-Skelly also within the starting XI and sent out to play in midfield.
Nonetheless, shortly before the beginning of the match there was a change to the Arsenal team, with Calafiori axed and Bukayo Saka brought into the starting XI.
Lewis-Skelly reverted to left-back, where he has played most often in the primary, team, while Saka appeared to maneuver right into a free role in midfield.
Ceadach O’Neill, the 17-year-old Northern Irish forward, was a late addition to the bench to switch Saka.
Calafiori began the season well for Arsenal, scoring against Manchester United on the opening day of the season and remaining an everyday within the starting line-up.
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Nonetheless, he picked up an injury in December and a month in the course of the busy festive period, before returning in late January.
That issue also happened within the warm-up, when he was attributable to play against Brighton within the Premier League but was pulled out and didn’t return until he played against Kairat within the Champions League on January 28.
When Calafiori began to struggle in December, Mikel Arteta said of the issue: ‘Something with Ricci was very, very strange.
‘It’s something that he felt yesterday, something very awkward that happened and today within the warm-up he wasn’t comfortable.’
He began for the primary time since December within the 3-0 win over Sunderland within the Premier League on February 7.
The character of the injury that has kept him out of the motion against Wigan on Sunday is yet to be disclosed.
Already sidelined for the Gunners are Mikel Merino, Kai Havertz and Max Dowman.
Centre-back William Saliba was out attributable to illness but has recovered and began the sport on Sunday against Wigan.
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